Common Female Hormone Disorder (PCOS)
Polycystic Ovary Syndrome is (PCOS) is a common female hormone disorder seen in women during their reproductive years (age group 16 to 40 years).
It affects about 20% of women. The affected women usually complain of
- Irregular menstrual cycles
- Extra facial and body hair
- Thinning of hair on scalp and
- Weight gain
The signs and symptom may begin soon after menarche and in some cases in response to weight gain.
The cause of this condition is still not clearly understood. PCOS results from hormonal disturbances in the body. Such women have higher incidence of insulin resistance which means that their ability to use insulin is impaired. Hence pancreas secretes more insulin which in turn interferes with ovulation. Also there is a hereditary factor to it. Women whose mother or sister has PCOS have a higher chance of getting effected.
These women may have difficulty in conceiving (Infertility).When carrying they have a higher incidence of miscarriage, gestational diabetes high blood pressure and a higher likelihood of having a premature delivery. Such women are prone to have type 2 Diabetes, Dyslipedimeas, high blood pressure and endometrial cancer in later life
Ultrasound is an important diagnostic too which when used in conjunction with clinical findings can help in diagnosing the condition.
- Lifestyle modification is one of the key aspect of managing patients with PCOS Women should aim at maintain a healthy weight by proper diet and exercise.
- Menstrual cycle regulation is done by using combination oral contraceptive pills or by using progesterone in the second half of the cycle.
- Use of Metformin improves insulin resistance
- Clomiphene Citrate is given to women who are anxious to conceive
Early diagnosis and treatment helps to prevent serious health problems such as Diabetes and cardiovascular disease.
Dr. Bandana, MBBS, DGO,
Apollo Hospitals, Secunderabad